Build it up-Tear it down: protein quality control in the cardiac sarcomere
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Build it up-Tear it down: protein quality control in the cardiac sarcomere.
The assembly and maintenance of the cardiac sarcomere, which contains the basic contractile components of actin and myosin, are essential for cardiac function. While often described as a static structure, the sarcomere is actually dynamic and undergoes constant turnover, allowing it to adapt to physiological changes while still maintaining function. A host of new factors have been identified th...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2008
ISSN: 0008-6363
DOI: 10.1093/cvr/cvn289